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The Many Roles of Oestrogen

When it comes to oestrogen the saying ‘you don’t know what you have until it’s gone’ applies. As women, we don’t always appreciate the importance of oestrogen until later in life when we’ve gone through the menopause and our oestrogen levels fall. It is then that we realise that the role of oestrogen goes beyond that of reproductive health. Oestrogen is a hormone that is produced mainly by the ovaries where it controls the onset of puberty, regulates our menstrual cycle and prepares our body for a successful pregnancy. These are the roles of oestrogen that we would expect but oestrogen has other very important functions and if we understand these we can better prepare for life after menopause. Outside of the female reproductive system oestrogen is very important in maintaining our bone density so that our bones are strong and healthy,  protecting us against heart disease and maintaining the health of our skin and hair.
Oestrogen and Our Bones
Oestrogen is instrumental in maintaining our bone mass ensuring we have strong bones that do not fracture easily. It carries out this role by controlling the activity of bone-forming cells called osteoblasts and bone-resorbing cells called osteoclasts.
When oestrogen is present it prolongs the life of bone-forming cells enabling these cells to initiate the process of bone formation. At the same time, oestrogen shortens the life span of the bone-resorbing cells which means that bone formation is the dominate process and this strengthens our bones.When oestrogen levels fall the balance reverses so the life span of bone-resorbing cells is prolonged leading to bone loss and brittle bones which fracture easily.After menopause oestrogen levels fall so women will be in a state where their body will be breaking down more bone than they are making.  Hence post-menopausal women are four times more likely to suffer from osteoporosis than their male counterparts.

You might find the video below useful in understanding the bone formation process.

Oestrogen and Cardiovascular Disease

Oestrogen is thought to protect us from cardiovascular disease in a diversity of ways, some of which include: improving the function of our blood vessels, preventing atherosclerosis (hardening of the arteries) and controlling immune reactions that are important in cardiovascular function. This contributes to the fact that premenopausal women are at lower risk of developing heart disease than their male counterparts.

When a woman goes through menopause the reduction in oestrogen as well as other factors (increases in blood pressure and changes in cholesterol and fat levels) increases her risk of developing heart disease.

Oestrogen, Skin and Hair

A number of studies over the years have shown that oestrogen plays a role in the health of our skin and hair, contributing to the following:

  • Maintaining skin thickness
  •  Protecting skin from photo-ageing and skin cancer
  • Accelerating wound healing
  • Retaining moisture in the skin
  • Stimulating hair growth

What this Means for  Menopause

Understanding the role of oestrogen means that we can predict some of the changes that will take place after the menopause. It also means that we can start making changes to our lifestyle to combat the major health concerns that are associated with menopause (osteoporosis and cardiovascular disease).

Adopting a healthy lifestyle before, during and after menopause can help lower our risk of osteoporosis and cardiovascular disease and all women should pay particular attention to developing a lifestyle that encourages a healthy heart and strong bones. This can be achieved by:

  1. Keeping active – women are less likely to suffer from severe post-menopausal osteoporosis if they are fit and active. This is because exercise helps strengthen our bones. In addition, keeping active helps maintain a healthy heart.
  2. Eating a diet rich in calcium (dairy products, green leafy vegetables,  oily fish and calcium-fortified foods) and don’t forget vitamin D as it helps us absorb calcium (sources of vitamin D include sunlight, oily fish, eggs, fortified cereals and fortified fat spreads).
  3. Eating a diet that is low in fat and high in fibre, fruit and vegetables.

In most cases, menopause will cause a number of symptoms that we haven’t discussed in this blog, to find out more about these read our previous blog or visit Menopause Matters’ website.

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